Genotoxicity test of irradiated foods

Chapter 4 TOXICOLOGICAL SAFETY OF IRRADIATED FOODS

Generation of cancers in animals requires the mutation or deletion of oncogenes or tumor suppressor genes, resulting in a loss of heterozygosity at those allele locations. Mutation (point mutations or frame-shift mutations) and deletion of genes can be induced by exposure of cells to genotoxic chemicals or can occur naturally as part of the cellular DNA repair and replication process (Ames and ...

EPR study of gamma – irradiated cereal foods

The results from the EPR studies on wheat and oat bran, rolled oats, buckwheat and different kind of rice – white, brown and parboiled rice before and after gamma-irradiation are reported. Before irradiation all samples exhibit one weak singlet EPR line characterized with common g-factor of 2.00480.0005 and six lines due to Mn naturally available in the plants. Only parboiled rice did not show...

Acrylamide in selected foods and genotoxicity of their extracts.

Acrylamide is one of the most important contaminants in the environment. Acrylamide was shown to be a neurotoxicant, reproductive toxicant, and carcinogen in animals. There is consensus among international food safety groups that acrylamide in the diet should be assessed. In the present study, we surveyed by Gas Chromatography-Mass Spectrometry (GC-MS) the levels of acrylamide in 23 foods marke...

Bioindicator of Genotoxicity: The Allium cepa Test

Solange Bosio Tedesco1,2 and Haywood Dail Laughinghouse IV3,4 1Graduate Program in Agrobiology, Department of Biology Universidade Federal de Santa Maria (UFSM), Santa Maria 2Graduate Program in Agronomy, UFSM, Santa Maria 3National Museum of Natural History, Smithsonian Institution, Washington, DC 4College of Computer, Mathematical & Natural Sciences University of Maryland, College Park, MD 1,...

Do irradiated foods cause or promote colon cancer?